Objective: Mitochondrial pyruvate is a critical intermediary metabolite in gluconeogenesis, lipogenesis, and NADH production.As a result, the mitochondrial pyruvate copyright (MPC) complex has emerged as a promising therapeutic target in metabolic diseases.Clinical trials are currently underway.However, recent in vitro data indicate that MPC inhibi
Global demand for vegetable oil and high oil palm yield have driven the rapid expansion of oil palm plantations in tropical countries.The research literature widely recognizes the effects of forest cover conversion into oil palm on biodiversity, deforestation, and carbon dynamics.However, research on the ecohydrological impacts of oil palm plantati
Summary: Response to multiple microenvironmental cues and resilience to mechanical stress are essential features of trafficking leukocytes.Here, we describe unexpected role of titin (TTN), the largest protein encoded by the human genome, in the regulation of mechanisms of lymphocyte trafficking.Human T and B lymphocytes express five TTN isoforms, e
The article addresses problematic issues arising when the fate of a civil DRY SHAMPOO DARK TONES claim cannot be determined in a criminal case considered in a court of first instance, as well as in cases of termination of a criminal case or criminal prosecution in pre-trial proceedings.The purpose of the study is to substantiate the idea of the nee
During tumorigenesis, miRNAs with unbalanced expression profiles can increase the threat of disease progression.Here, we focus on the role of miR-331-5p in the pathogenesis of thyroid cancer (TC).In vitro studies were conducted using TC cell lines after the forced expression and silencing of miR-331-5p.Cell proliferation and viability were analyzed